[three_fourths]
Summary of Abstract: 0-180
Background and Significance
Case reports describing children conceived via ICSI developing a very rare form of an imprinting disorder, Angelman syndrome (AS), were published in 2002 and in 2005 (Cox et al, 2002;Ludwig et al, 2005). Following these case reports three independent studies have described increased frequencies of the imprinting disorders AS and Beckwith-Wiedemann syndrome (BWS) in children conceived via assisted reproductive technology (Debaun et al, 2003; Maher et al, 2003; Gicquel et al, 2003)….
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