CRB Abstract: A comparison of DNA damage between vitrified and slow-cooled mouse embryos
The objective of this study is to determine if there is more DNA damage caused by freezing with vitrification or a slow-cooled method.
This was a randomized, prospective, pilot study with two-cell mouse embryos (B6C3F1). Vitrified embryos were exposed to a holding solution then a vitrification solution that consisted of Dulbecco’s Phosphate Buffered Saline without calcium and magnesium, ethylene glycol and dimethyl sulfoxide…
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