Does Laser Assisted Hatching Using Partial Zona Thinning (LAH) Improve Outcome In Frozen Embryo Transfer (FET) Cycles?

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Does Laser Assisted Hatching Using Partial Zona Thinning (LAH) Improve Outcome In Frozen Embryo Transfer (FET) Cycles?

Objective
Frozen embryo transfer (FET) cycles involving cleavage- stage embryos generally have a lower pregnancy outcome compared to transfers involving fresh embryos. This may be due, in part, to zona pellucida hardening during the cryopreservation process and subsequent failure of the embryo to hatch, thereby preventing effective implantation. Assisted hatching (AH) may improve implantation in cases where embryos fail to hatch from the zona pellucida. In some centres, all patients scheduled for FET are offered AH, but its value in such cases is not clear….
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