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Current Methods for Preimplantation Genetic Diagnosis
Introduction
Couples undergoing in vitro fertilization (IVF) (1) have the unique opportunity to use pre-implantation genetic diagnosis (PGD) to select their best embryos for transfer, maximizing their chances of a successful pregnancy and the birth of a healthy child. In the 20 years since the first PGD babies were born (2), the technologies that have been available to fertility practitioners have advanced considerably.
PGD was originally applied to couples with a family history of known genetic disease that wished to avoid conceiving an affected child. Such application…
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